WORKSHOP: Requirements for a Digital Therapeutics (DTx) Design and Trial Service: An Expert Workshop Har passerat
Tisdag 23 maj 2023 15:45 - 17:15 R23
Föreläsare: Kerstin Denecke, Tobias Kowatsch
Spår: MIE: Special Topic: Caring is Sharing - exploiting value in data for health and innovation
Non-communicable diseases (NCDs), such as diabetes, hypertension, asthma, cancer or cardiovascular diseases, and common mental disorders (CMDs) including neurodegenerative diseases such as depression, anxiety or dementia lead to substantial health and economic burdens [1-9]. Risk factors related to NCDs and CMDs are smoking, excessive alcohol consumption, malnutrition, physical inactivity, overweight and obesity, and high levels of blood pressure, cholesterol, and glucose [10-12].
Digital therapeutics (DTx) are "evidence-based therapeutic interventions that are driven by high-quality software programs to prevent, manage, or treat a medical disorder or disease."  DTx have the potential to reduce the burden of NCDs and CMDs [2, 14]. Today, however, DTx are often limited in their scope and usefulness (e.g., DIGAs in Germany ) as they focus primarily on one social actor – the patient – and do not consider the orchestration of the broader social system (family, friends, or peers of patients) or more complex care cases that require multiple professions (e.g., patients suffering from multiple NCDs/CMDs) . Especially the latter cases of multi- morbidity are getting increasingly important due to the aging population [3, 4, 17, 18]. These demographic trends also require new DTx technologies that are beyond today’s paradigm of web- or smartphone-based DTx, such as scalable voice assistants [19, 20], to increase access to healthcare services esp. in individuals with physical or mental disabilities. Moreover, the design and evaluation of DTx requires a significant amount of expertise in various areas, such as medicine, health and clinical psychology, software engineering, computer science, ethics, and regulation . Moreover, each DTx requires a robust technology stack that supports DTx designers and other stakeholders, such as physicians, caretakers, and patients.
To this end and as a first step, it is of utmost importance to understand better the requirements for a DTx design and trial service that supports the design of DTx and their efficient evaluation via feasibility studies, optimization trials (e.g., micro-randomized trials), efficacy or effectiveness trials (e.g., randomized controlled trials). This workshop has, therefore, the objective of gathering such requirements by applying the World Café methodology and discussing several complex care scenarios. We welcome participants with various backgrounds (e.g., technical, regulatory, medical, ethical) who bring in different perspectives.
The following outcomes of this workshop are expected:
List of requirements for a DTx design and trial service, esp. for complex care scenarios (immediate outcome)
Scientific article on these requirements (mid-term outcome; interested participants who participate in follow-ups will be offered co-authorship)
Community of experts interested in DTx design and trial services (mid-term outcome)
Collaborative design, implementation, and maintenance of a globally scalable DTx design and trial service (long-term outcome)
Introductions (5 min, all participants)
Motivating the workshop (15 min, workshop chairs)
Requirements gathering with World Café methodology (30 min, all participants, moderation by workshop chairs)
Presentation of the findings (20 min, workshop chairs)
Wrap-up and next steps (10 min, workshop chairs)
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Enbart på plats
Tobias Kowatsch, Kerstin Denecke
Kerstin Denecke Föreläsare
Bern University of Applied Sciences
I am a researcher in medical informatics, focussing on natural language processing, participatory health informatics, chatbots.
Tobias Kowatsch Föreläsare
University of Zurich, University of St.Gallen, ETH Zurich
- Digital therapeutics for healthy longevity (e.g., metabolic health interventions)
- Digital health interventions (e.g., just-in-time adaptive interventions)
Digital clinical pathways and working alliance between patients, relatives, health professionals and digital coaches (e.g., conversational agents, voice assistants)
- Digital biomarker (e.g., detection of biological age, emotional states, stress, breathing)
Prof. Dr. Tobias Kowatsch is Associate Professor for Digital Health Interventions at the external pageInstitute for Implementation Science in Health Carecall_made, external pageUniversity of Zurichcall_made (UZH), and Director at the external pageSchool of Medicinecall_made, external pageUniversity of St.Gallencall_made (HSG). He is also the Scientific Director of the external pageCentre for Digital Health Interventionscall_made, a joint initiative of UZH, HSG, and ETH Zurich. Moreover, Dr. Kowatsch is an advisor to the external pageCenter for Technology and Behavioral Healthcall_made at Dartmouth, USA, and Lead Principal Investigator for Mobile Health Interventions within the Future Health Technologies Programme at the Singapore-ETH Centre.