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U-Net-based segmentation of current imaging biomarkers in OCT-scans of patients with age related macular degeneration Passed

Wednesday May 24, 2023 11:00 - 11:15 G2

Lecturer: Mustafa Kemal Yildirim

Track: MIE: Sensors, signals and Imaging Informatics

Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. In this work, the non-invasive imaging technique spectral domain optical coherence tomography (SD-OCT) is used to acquire retinal images, which are then analyzed using deep learning techniques. The authors trained a convolutional neural network (CNN) using 1300 SD-OCT scans annotated by trained experts for the presence of different biomarkers associated with AMD. The CNN was able to accurately segment these biomarkers and the performance was further enhanced through transfer learning with weights from a separate classifier, trained on a large external public OCT dataset to distinguish between different types of AMD. Our model is able to accurately detect and segment AMD biomarkers in OCT scans, which suggests that it could be useful for prioritizing patients and reducing ophthalmologists' workloads.

Language

English

Seminar type

On site only

Level of knowledge

Advanced

Conference

MIE

Authors

Kemal Yildirim, Sami Al-Nawaiseh, Sophia Ehlers, Lukas Schießer, Michael Storck, Tobias Brix, Nicole Eter, Julian Varghese

Lecturers

Profile image for Mustafa Kemal Yildirim

Mustafa Kemal Yildirim Lecturer

Research Associate
University Muenster, Germany

I am part of the Institute of Medical Informatics in Münster, Germany. I completed my Bachelor's (2012-2016) and Master's (2016-2018) in Medical Informatics at the Ruprecht-Karls-Universität Heidelberg, where I cultivated a strong interest in Computer Vision in healthcare.
As a Research Associate and PhD student in the Department of Ophthalmology at the University Hospital Münster, my research focuses on AI-assisted support in ophthalmic diseases. I am dedicated to developing innovative solutions to improve patient outcomes and transform the field of ophthalmology.