Background: A person-centred approach to healthcare in nursing homes can boost patient satisfaction and perception of care quality and contribute to higher job satisfaction among healthcare staff. Leaders hold a significant role in shaping the culture within nursing homes, crucial for the successful implementation and maintenance of a person-centred practice. While there exists some empirical evidence, a more comprehensive understanding is needed of how leaders foster and maintain person-centred practice in this setting. Aim: To identify the underlying leadership dynamics that facilitate the adoption and maintenance of a person-centred practice in nursing homes, informed by both leadership and staff insights. Methods: A systematic review was conducted using the Joanna Briggs Institute Methodology. Relevant articles were selected based on predefined criteria. Rayyan software was utilized for article screening and selection. Results: Ten studies, comprising five qualitative and five quantitative, were included in the review. The analysis yielded three core themes. First, leadership defined by a collectively endorsed vision for person-centred practice emerged as a central dynamic. Second, the importance of a consistent and systematic approach to realizing person-centred outcomes was underscored. Lastly, it was revealed that leaders play a pivotal role in leading by example, embodying person-centred values through their actions. Conclusions: The significance of leadership in facilitating the adoption and maintenance of a person-centred practice in nursing homes is confirmed by this systematic review. The leadership dynamics hinge on a collective vision, methodical pursuit of person-centred outcomes, and role-model behaviours. The role of leaders in setting and exemplifying person-centred values in nursing homes is paramount. These findings synthesize the existing body of knowledge, offering key findings that enhance our understanding and provide valuable insights for nursing home leaders and policymakers seeking to enhance person-centred practice in healthcare.