Background: The Person-centred Practice Framework (1) represents a cornerstone for practice development in healthcare and gets increasingly common. To measure the effect the Person-Centred Practice Inventory—Staff (PCPI-S) is used. It measures clinicians’ experience of a person-centred culture in English language (2). Method: A cross-sectional observational study followed the guidelines of good practice for the translation and cross-cultural adaptation (3). First step involved the translation and cultural adaptation to the acute care setting. For the second step, psychometric retesting and statistical analysis based on a quantitative cross-sectional survey were undertaken. To evaluate the construct validity, a confirmatory factor analysis was implemented. Cronbach’s alpha was used to determine the internal consistency. Further a consensus conference took place with experts in the field form Austria, Germany, and Switzerland, to culturally adapt the person-centered practice framework and related models and concepts into German language. Results: A sample of 711 nurses in a Swiss acute care setting participated in the study. Confirmatory factor analysis indicated a good overall model fit, validating the strong theoretical framework, which underpins the PCPI-S aG Swiss. The results the harmonized translations are crucial for the further development of person-centerd practice in German spoken countries. Conclusion: The chosen procedure ensured cultural adaptation to the German-speaking part of Switzerland. The psychometric results were good to excellent and comparable with other translations of the instrument. Discussion: As a result, the importance of the use of language and words in fostering a common understanding has been showed. In this presentation the procedure for translating and the culturally adapting the PCPI-S will be presented. Furthermore, it will illustrate how to organize a process to achieve a harmonized translation. The experiences of these three nations can serve as a role model for other countries facing with similar challenges.