Health outcomes are influenced by our health care, social, governmental, economic, and environmental systems — all dimensions of the Sustainable Development Goals. Achieving these goals requires a broadened application of person-centered care across health systems. Indeed, person-centered care plays a fundamental role in shaping people’s trust and confidence in the health system and affects health outcomes across the life course. In this session, we will provide an overview of JSI’s person-centered care framework, which is theoretically based in the socioecological model and includes five principles and six domains derived from literature and practice. We will discuss how the framework can be used to improve the design, management, delivery, and measurement of global health programs that are shaped by and responsive to the needs of individuals and communities. Using country examples across contexts (Ethiopia, Zambia, Ghana, and Nepal) and health areas (maternal health, immunization, and HIV/AIDS), we will discuss how we have applied person-centered care more broadly across health systems and communities. We will use the person-centered care framework as the guide for our discussion. We will hold time for facilitated discussion with the audience to learn more about the application of person-centered care globally and to gather feedback on JSI’s framework. We will close with a call to action for how we can collectively advance person-centered care and other relevant approaches in order to achieve global goals of health and well-being for all.