This presentation offers a succinct exploration of cybersecurity integration in medical device manufacturing. It emphasizes the importance of embedding cybersecurity from the design phase, guided by the principles in IEC 81001-5-1. We will navigate through the various international regulatory landscapes, including the EU's MDR, U.S. FDA guidelines, and Japan's cybersecurity framework, highlighting their convergence with IEC 81001-5-1. The presentation emphasizes proactive, continuous cybersecurity measures in the evolving medical device sector that is faced with increasingly sophisticated threats.