Background: Suicidality reflects the interplay of physical, emotional, social and cultural dimensions of life. A person-centred approach seeks to understand these experiences holistically, moving beyond reductionist models to consider the full spectrum of human complexity and inform the development of tailored care. Aim: To examine differences in wishing to die among people with diverse health experiences and social determinants of health (SDOH). Methods: Data were obtained via the 2023-24 Canadian Equitable People-Centred Health Measurement survey which included a question on “wishing you were dead and away from it all” (N = 9691). Ordinal logistic regression models were used to examine associations between wishing to die and physical and mental health experiences, emotional wellbeing, and SDOH. Findings: Most participants identified as White (71%), 55% identified as women, 14% reported having difficulty paying for basic needs and 26% had an undergraduate degree or some university. In response to the wishing to die question, 76% of participants indicated ‘none of the time’, 13% ‘a little of the time’, 7% ‘some of the time’, and 4% ‘most or all of the time’. Wishing to die was associated with several SDOH, including education, race, and housing situation. For example, having completed no formal school, having any disability, identifying as non-White, and homelessness were associated with increased time spent wishing to die. The odds ratio (OR) of increased wishing to die while having poor or fair physical health, as compared to excellent physical health was 5.0. The OR of increased wishing to die while having poor or fair mental health, as compared to excellent mental health, was 29.7. Conclusion: This study highlights the multifaceted nature of suicidality and the need for person-centered care interventions that address not only clinical symptoms but also pay attention to broader social and cultural contexts of psychological distress.