Background The Danish healthcare system increasingly emphasizes proximity, equity, and continuity to ensure that care remains meaningful, accessible, and coherent for all citizens. In a complex and fragmented landscape, person-centred care (PCC) offers a strategic approach to achieve these ambitions by grounding practice in relationships, co-creation, and meeting patients and families care needs. Three regional initiatives in Denmark illustrate structured, practice-oriented PCC approaches: Person-Centred Practice framework (Zealand University Hospital), Fundamentals of Care framework (North Denmark Region) and Excellent Nursing Care framework (Lillebaelt Hospital). Each region seeks to embed these core principles by anchoring care in holistic, relational, and integrated practice. Aim To explore how PCC frameworks can advance the goals of proximity, equity, and continuity in clinical practice, and to identify key factors to their successful implementation. Methods A narrative synthesis was conducted, drawing on research and experiences from clinical leaders, frontline care professionals, students and researchers from the three regions. These were integrated to explore how the PCC frameworks influence practice, and what contextual factors support or constrain their impact. Results PCC frameworks provide coherence and a shared professional language, supporting care that is closer to patients, more equitable, and better connected across settings. They foster professional identity, reflective team processes, and interdisciplinary collaboration. Yet, despite these benefits, implementation remains challenging. On the micro level, time constraints, staff turnover and competing priorities can undermine PCC. At the meso level, organisational silos and inflexible workflows may hinder collaboration and continuity. On the macro level, policy demands, performance metrics, and resource constraints can conflict with the values underpinning PCC.    Conclusion PCC frameworks act as catalysts for translating healthcare ambitions into coherent, meaningful practice. Successful integration of PCC requires leadership commitment, continuous organisational investment and strategic alignment across micro-, meso-, and macro-levels of the healthcare system.