Background: Today’s cancer care risks being system-focused, operating in an environment with little regard for patient’s life experiences or room for their participation. A person-centred approach, which promotes a continuous, trusting care relationship and considers patients’ unique situations, improves the well-being of both patients and healthcare professionals by increasing hope, enhancing communication, satisfaction, and engagement. Aim: To gain a deeper understanding of healthcare professionals’ experiences of possibilities and limitations for providing person-centred care, to alleviate suffering among patients within cancer care. Methods: A qualitative and exploratory design was used. Data were collected through four focus group interviews with 15 nurses and physicians from a cancer clinic in Finland. A qualitative content analysis was used to analyse the data material. Results: Healthcare professionals’ internal motivation and knowledge are comprehensive. However, their ability to provide person-centred care is limited by organisational structures, such as time constraints, strict management, and resource availability. These issues cause failure demand and limit the ability to create meaningful and long-term care relationships with patients, and can lead to feelings of powerlessness and ethical stress among healthcare professionals when they cannot provide the care they believe is best for their patients. Conclusions: There is a need for more integration in the healthcare organisation, through better collaboration and flexibility between different instances. This could reduce failure demand and release resources. By gaining a deeper understanding of the problems and addressing them together, healthcare professionals’ ability to provide high-quality person-centred care can be enhanced, ultimately reducing patient suffering and improving their well-being. Keywords: person-centred care, cancer care, healthcare professionals, organisational structures, work environment, qualitative study