Background: People with chronic heart failure face a complex condition that profoundly affects their health outcomes due to symptom burden and psychological factors. Implementing a person-centered care (PCC) approach involves shifting toward a care model that prioritizes patients’ preferences and encourages their active participation in care planning and decision-making. Aims: To evaluate the effectiveness of a person-centered care (PCC) intervention, delivered both face-to-face and by telephone, in addition to standard care, compared with conventional care, on the use of health services among people with chronic heart failure. Setting: Three outpatient heart failure units in Spain. Design: A multicenter randomized controlled trial was conducted following the new MRC framework for complex interventions. The study was guided by a program theory and logic model, and co-created with patients and clinicians. Statistical analyses were performed using linear mixed models (LMM) to assess changes over time and between groups, accounting for individual variability. Point plots with error bars were used to visualize score trajectories across time points (t0, t1, t2), helping to illustrate group differences. Results: The PCC group achieved better clinical outcomes. Unplanned hospitalizations decreased from 18% to nearly zero (p = 0.007), and unplanned emergency visits dropped from 40% to almost none (p = 0.023). Decompensations also declined significantly at t2 (p = 0.024), with greater reductions in the PCC group. Regarding EHFScB-9-based self-care behaviors, both groups improved, but the PCC group showed a stronger increase (p = 0.001). Conclusion: The sharper decline in emergency events among PCC participants suggests they were better able to recognize symptoms early, take timely action to manage their condition, and may have developed stronger relationships with their care team. Overall, these findings highlight the potential of person-centered care to enhance clinical stability and empower patients to manage chronic heart failure more effectively.