Clinical Decision Support (CDS) is shifting from proprietary rule engines to FHIR-based architectures. This evolution enables organizations to design, publish, and maintain portable knowledge artifacts – from computable guidelines expressed with CPG/CQL to FHIR Quality Measures and CDS Hooks services – that can be shared across sites, systems, and country borders.

This session provides an overview of FHIR‑based CDS and shares pragmatic examples. We will discuss how the European Health Data Space (EHDS) could reduce friction for cross-border FHIR-based CDS and conclude with a call to action for Nordic collaboration.