Ventilation based on total volume air distribution in spaces is not always an efficient way to provide occupants with high air for breathing at low-energy consumption. This talk justifies the need for improving the present air distribution design in spaces, and in general the need for a paradigm shift from the design of present ventilation methods to design of advanced ventilation focused on control of supplied air distribution providing each occupant with clean air for breathing. Examples of advanced air distribution solutions in spaces for different use, such as offices, hospital rooms, vehicle compartments, etc. are presented. The potential of controlled air distribution for improving health and comfort of ach occupant at reduced energy consumption is demonstrated. Design criteria are defined and further development is outlined.