Background: A previous mixed-method systematic review synthesized evidence on clinicians’ experiences with patient-reported outcome measures (PROMs) and factors influencing PROMs integration into practice. To implement this evidence, a researcher-knowledge user partnership was formed within a health region providing community mental health and substance use services. This project aimed to engage stakeholders to co-develop (i) a toolkit for clinical leaders to equip point-of-care staff to integrate the World Health Organization Quality of Life assessment tool into practice, and (ii) resources for managers to address factors influencing the uptake of PROMs by clinicians. Methods: A collaborative partnership, involving researchers, knowledge users (KUs), and a patient partner, was formed based on the principles of Integrated Knowledge Translation and transformational leadership. Two implementation science theories (i.e., Theoretical Domains Framework (TDF) and the Capability, Opportunity, Motivation and Behaviour System (COM-B)) guided all aspects of the project to tailor the evidence to the local context and intentionally select effective strategies for practice change. Several activities were conducted to involve the practice influencers, such as needs assessments and small group discussions. Results: We identified several resources for clinical leaders and information needs of managers to have conversations with their teams. We developed a Toolkit including six types of practice-based resources designed to meet the needs of end-users by being practical, relevant, and accessible. These resources not only focus on capacity-building but, more importantly, the motivations (beliefs and attitudes) and implementation supports for routine use of the WHOQOL by clinicians. Conclusion: Co-development of KT strategies to implement research evidence by targeting clinical leaders and managers is an important equip point-of-care staff and sustain change at the micro level. These outputs are designed to improve knowledge, shape attitudes, and address environmental supports for knowledge users, thereby fostering equitable person-centred recovery planning for persons living with a mental illness.