Over the past decade, a neuro-oncology nursing group at Rigshospitalet has been dedicated to advancing a person-centred and family-focused approach to care for people with brain cancer and their families.  Being diagnosed with a malignant brain tumor is a life-altering event that often leads to significant physical, cognitive, psychological, and psychosocial changes for the patient. These changes place increased demands on close relatives, who are often required to take on substantial responsibilities in managing the patient’s care and treatment. No two brain cancer trajectories are alike, as tumor location and individualised symptom response result in highly diverse patient profiles. Therefore, it is essential to align care and treatment decisions with each patient's unique needs and preferences, and this must be at the heart of everything healthcare professionals do. This presentation focuses on implementing person-centred clinical practice, exploring both the barriers and facilitators within a multidisciplinary setting. In this presentation, examples of how a family-focused model can be implemented in a large cancer centre will be explored.   To tailor guidance and support for these patients and their families, the neuro-oncology nursing group has:  Identified patients’ and caregivers’ needs and preferences longitudinally  Implemented Family Conversations in an outpatient clinic.  Measured the Caregivers' Role and Responsibility level among the close caregivers  Explored caregivers’ often hidden and tabooed thoughts when living with a person suffering from personality changes due to a brain tumor.    This research, along with insights from clinical practice, will be further explored to inspire colleagues interested in implementing a person-centred care model tailored to the needs of a specific population.