Background: As healthcare continues to transition toward a more proactive and person-centered approach, there is growing recognition of the importance of empowering individuals to self-manage the consequences of their long-term health conditions in activities of everyday life. However, incorporating such proactive person-centered self-management support that aligns with individuals’ needs has proven challenging. For healthcare to succeed in this transition, it is important to improve the understanding of how self-management support is experienced by both individuals living with long-term health conditions and the healthcare professionals involved. Aims/Objectives: To explore the experience of proactive person-centered self-management support for activities in everyday life among individuals with long-term health conditions and healthcare professionals. Methods: A qualitative focus group study was designed. Five focus group discussions were conducted: two with patient organizations and three with healthcare professionals, including managers. Data was analyzed using a focus group analysis to identify shared and divergent experiences. Results: The resulting themes illustrate that both individuals with long-term health conditions and professionals experienced difficulties navigating in healthcare to enable timely self-management support for activities in everyday life. Self-management support was often introduced late in the disease trajectory and tended to focus on generic, diagnosis-related advice rather than on individuals’ specific self-management needs in everyday life. The access to self-management support was hindered by insufficient person-centeredness, absence of systematic routines for identifying needs, limited resources, and insufficient knowledge of available support. Conclusions: The findings highlight the need for healthcare to develop proactive, person-centered processes, including early and individualized screening for self-management needs related to activities in everyday life. Aligning individuals’ self-management needs with available support requires better dissemination of information about available self-management interventions to both citizens and professionals. Enhanced access to such information has the potential to facilitate timely tailored self-management support in everyday life.