Background and Objectives: Using patient experience data (PXD) to improve healthcare quality is gaining interest, but it rarely translates into improvements in patient care. Recognizing the organizational challenges (e.g., competing priorities, data interpretation uncertainty) to collecting and actioning PXD, we aimed to understand related facilitators and barriers to identify strategies to overcome these hurdles in a hospital setting. Approach: Our team conducted a qualitative descriptive study with 23 participants (10 patient and caregiver partners, 13 hospital staff) from a multi-site, urban hospital in southern Ontario, Canada. Interviews and focus groups were held. Interview questions were guided by a four-part schematic created by our team outlining a potential strategy to action PXD. The five domains of the Consolidated Framework for Implementation Research (CFIR) were used to develop our codebook and guide analysis: Innovation, Outer and Inner Setting, Individuals and Implementation Process. Results: Participants provided reflections on the PXD strategy. Our findings were organized using the CFIR domains. For Innovation, participants identified the need to have clear goals and outcomes. For Inner and Outer Setting, participants emphasized the importance of understanding how external (e.g., seasonal illness, policy changes) and internal constraints (e.g., accreditation, staff burnout) affect implementation. At the Individual level, the perception among staff that implementation was not feasible in their day-to-day work was a barrier. Participants emphasized the co-collaboration between patients, caregivers and hospital staff (e.g., leadership, front-line staff, service workers) to implement improvement initiatives as a key facilitator for the Implementation Process. Conclusion: The CFIR constructs served as a useful analytic frame for identifying factors that support acting on PXD to create a more responsive, person-centred healthcare system. This requires a strong organizational commitment, a concrete strategy, a culture that values patient experience, meaningful collaboration, and clear accountability. Our findings can be further tested in a future implementation study.