Presentation

The powerful neurosteroid Allopregnanolone (ALLO) is implicated in a wide range of stress- and compulsion-related conditions from menstrual migraine to Tourette, OCD, PTSD, PMDD, compulsive gambling, addiction—and more.​ Asarina´s novel treatment Sepranolone is the endogenous compound that inhibits and modulates ALLO. It is the first of a new family of GAMSA compounds (GABAA Modulating Steroid Antagonists). GAMSAs target the powerful neurosteroids that act on the brain’s GABAA receptors. GAMSAs represent a new paradigm shift in the treatment of still widely untreated stress- and compulsion-related conditions.